Did you know the Institute of Health Metrics and Evaluation predicts neck pain cases are projected to reach 269 million by 2050? In other words, we may witness a 32.5% increase in patients with neck-related complications alone, a significant hike in prevalence.
As a result, clinicians continue to rely on various diagnostic and interventional pain management techniques to help patients. One commonly reported interventional pain management procedure is described by CPT code 62321.
It involves an interlaminar epidural injection performed with imaging guidance for diagnostic or therapeutic purposes. Let’s look at the procedure in more detail.
CPT Code 62321 – Description
The CPT code 62321 covers a pain management procedure in which a medical practitioner injects a therapeutic or diagnostic substance into the cervical or thoracic epidural space, using CT or fluoroscopy. In this procedure, a needle is inserted into the region to facilitate the administration and reduce pain via medication.
When is This CPT Code Commonly Used?
This procedure is most commonly used for pain management, where epidural steroid injections are administered. Again, the procedure is performed under real-time imaging, allowing physicians to guide needle placement for accurate substance administration.
Note that Medicare covers this procedure. However, reimbursement is not guaranteed unless all the billing requirements are fulfilled. Thus, proving medical necessity through accurate documentation is a must for successful and timely claim acceptance.
Medical practitioners administer substances or agents, such as corticosteroids and anesthetics, to the epidural region, depending on the patient’s medical condition.
What Do the Current Requirements Dictate?
In 2019, the CPT code set for epidural injections was revised. Imaging guidance (fluoroscopy or CT) is required and bundled into the code, and contrast injection is included when performed. Meaning, they should no longer be reported separately while billing the payer.
Cases Where CPT Code 62321 Applies
The following are three medical scenarios where the CPT code 62321 applies for reimbursement:
Pain Management
Consider a 66-year-old female patient who develops sharp neck pain radiating to the right arm after lifting heavy items at home. She appears at the physician’s clinic, explaining her medical condition and history.
As the medical practitioner observes no improvement after physical therapy, he takes another route.
He performs a fluoroscopy-guided cervical epidural steroid injection. The service is reported using CPT 62321. The patient experiences a reduction in nerve inflammation and improvement in function.
Finally, the service is reported with CPT code 62321 for precise billing.
Cervical Radiculopathy Due to Disc Herniation
Imagine a 52-year-old female who experiences persistent shoulder pain and arm tingling. She arrives at the medical facility and explains her condition to the physician. The physician orders an MRI, which reveals a bulging cervical disc.
Therefore, the physician performs a cervical epidural injection using CT imaging guidance to alleviate nerve compression. The billing team then uses CPT code 62321 to bill the payer for services.
Thoracic Spinal Stenosis
Consider a 65-year-old male suffering from chronic mid-back pain because of degenerative changes leading to ligament thickening over the years.
The patient complains of this to the physician, who suspects thoracic spinal stenosis pinching nerves after evaluation, limiting the patient’s daily activities. Thus, the practitioner initially prescribes oral painkillers, but the patient does not feel an improvement in the pain levels.
Therefore, after observation, the physician administers an imaging-guided epidural steroid injection (billed under CPT code 62321). The injection is administered into the thoracic region for pain relief.
Modifiers to Append with CPT Code 62321
Modifiers play a crucial role when reporting CPT 62321, and misusing them during billing can lead to denials or delays. The following are the modifiers to know:
Modifier 59
Modifier 59 may be used to indicate a distinct procedural service when an interlaminar epidural injection (represented with CPT 62321) is administered independently from other procedures performed on the same day. Note that modifier 59 is only allowed when these procedures would otherwise be bundled as per NCCI edits.
Modifier 76
Modifier 76 explains a repeat procedure in medical billing. This repeated procedure must be performed by the same physician on the same day due to medical necessity.
Modifier KX
Modifier KX indicates that the medical professional has met the requirements specified by the payer and that supporting documentation is available in the medical record.
Reimbursement Guidelines for CPT Code 62321
Successful medical billing with CPT code 62321 requires following the reimbursement guidelines precisely. Below are some guidelines medical professionals should remember:
Provide All Necessary Documents
Medical practitioners must always prove medical necessity with test reports and screenings. They should also showcase the failure of conservative treatment (i.e., physical therapy and NSAIDs). Additionally, the billing details should also include:
- Pain relief percentages before and after the procedure.
- Details of imaging guidance and needle placement with CT and fluoroscopy.
- Functional assessment and pain scores.
- Final needle position and contrast flow.
Consider Frequency Limitations
Generally, patients can get 4 epidural injections in the same region within 12 months, irrespective of the levels treated. However, there are exceptions based on policy differences. For example, Medicare and UnitedHealthcare follow this rule, but other commercial payers may not.
More importantly, exceeding these limitations during treatment will likely result in claim rejection.
Re-Check for Payer-Specific Details
Since billing and reimbursement policies might vary for each payer, billing teams should remain mindful of these changes before filing a reimbursement claim.
NeuraBill Offers Pain Management Billing Support
Billing payers for pain management services, such as an interlaminar epidural injection (CPT code 62321), can be confusing because of changing reimbursement rules.
If your medical practice is drowning in denials or experiencing a claim submission backlog, our pain management billing services are for you. We help you meet payer reimbursement requirements in a timely and efficient manner.
FAQs
What is the difference between CPT code 62321 and 62323?
CPT codes 62321 and 62323 both cover image-guided epidural injections, but for different regions. 62321 is for upper or mid back injections, whereas 62323 is applicable for lower back (lumbar or sacral) injections.
Can CPT code 62321 be billed with CPT code 72275?
No, CPT code 62321 cannot be billed with code 72275 because the former is a deleted code. Even if 72275 was an active code, you would not be able to bill it with 62321 because the latter already includes imaging guidance. Hence, fluoroscopy, or CT, is a part of the procedure and cannot be billed separately.


